USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: LMNB2_HUMAN USC-OGP 2-DE database:  LMNB2_HUMAN LMNB2_HUMAN General information about the entry View entry in simple text format Entry name LMNB2_HUMAN Primary accession number Q03252 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Lamin-B2; Flags: Precursor;. Gene name Name=LMNB2 Synonyms=LMN2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1133: pI=5.37; Mw=64830 Cross-references UniProtKB/Swiss-Prot Q03252; LMNB2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name LMNB2_HUMAN Primary accession number Q03252 Secondary accession number(s) O75292 Q14734 Q96DF6 Sequence was last modified on  November 11, 2015 (version 4) Annotations were last modified on  March 15, 2017 (version 176) Name and origin of the protein Description RecName: Full=Lamin-B2; Flags: Precursor; Gene name Name=LMNB2 Synonyms=LMN2 Encoded on Name=LMNB2; Synonyms=LMN2 Keywords 3D-structure; Acetylation; Coiled coil; Complete proteome; Direct protein sequencing; Disease mutation; Epilepsy; Intermediate filament; Isopeptide bond; Lipoprotein; Membrane; Methylation; Nucleus; Phosphoprotein; Polymorphism; Prenylation; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL BT007441; AAP36109.1; -; mRNA EMBL AC011522; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC005624; AAC34573.1; -; Genomic_DNA EMBL BC006551; AAH06551.1; ALT_INIT; mRNA EMBL M94362; AAA80979.1; -; mRNA EMBL M94363; AAB00873.1; ALT_SEQ; Genomic_DNA CCDS CCDS12090.2; -; . RefSeq NP_116126.3; NM_032737.3; . UniGene Hs.538286; -; . PDB 2LLL; NMR; -; A=469-589 PDB 5BNW; X-ray; 2.40 A; D=403-415 PDBsum 2LLL; -; . PDBsum 5BNW; -; . ProteinModelPortal Q03252; -; . SMR Q03252; -; . BioGrid 124281; 34; . DIP DIP-57724N; -; . IntAct Q03252; 38; . MINT MINT-3024955; -; . STRING 9606.ENSP00000462730; -; . iPTMnet Q03252; -; . PhosphoSitePlus Q03252; -; . SwissPalm Q03252; -; . BioMuta LMNB2; -; . DMDM 23503078; -; . REPRODUCTION-2DPAGE IPI00009771; -; . EPD Q03252; -; . MaxQB Q03252; -; . PaxDb Q03252; -; . PeptideAtlas Q03252; -; . PRIDE Q03252; -; . DNASU 84823; -; . Ensembl ENST00000325327; ENSP00000327054; ENSG00000176619; . GeneID 84823; -; . KEGG hsa:84823; -; . CTD 84823; -; . DisGeNET 84823; -; . GeneCards LMNB2; -; . GeneCards MIR7108; -; . HGNC HGNC:6638; LMNB2; . HPA HPA047863; -; . HPA HPA062477; -; . MalaCards LMNB2; -; . MIM 150341; gene; . MIM 608709; phenotype; . MIM 616540; phenotype; . neXtProt NX_Q03252; -; . OpenTargets ENSG00000176619; -; . Orphanet 79087; Partial acquired lipodystrophy; . PharmGKB PA30404; -; . eggNOG KOG0977; Eukaryota; . eggNOG ENOG410Y2H6; LUCA; . GeneTree ENSGT00830000128282; -; . HOGENOM HOG000007711; -; . HOVERGEN HBG013015; -; . InParanoid Q03252; -; . KO K07611; -; . OMA FRKNVFE; -; . TreeFam TF101181; -; . ChiTaRS LMNB2; human; . GenomeRNAi 84823; -; . PRO PR:Q03252; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000176619; -; . CleanEx HS_LMNB2; -; . GO GO:0005638; C:lamin filament; IEA:Ensembl; . GO GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell; . GO GO:0005198; F:structural molecule activity; IEA:InterPro; . Gene3D 2.60.40.1260; -; 1; . InterPro IPR001664; IF; . InterPro IPR018039; Intermediate_filament_CS; . InterPro IPR001322; Lamin_tail_dom; . PANTHER PTHR23239; PTHR23239; 1; . Pfam PF00038; Filament; 1; . Pfam PF00932; LTD; 1; . SMART SM01391; Filament; 1; . SUPFAM SSF74853; SSF74853; 1; . PROSITE PS00226; IF; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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